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Thursday, December 28, 2017

Cholesterol: the band aids of the body

Some of you might be aware that the FDA recently stated that cholesterol consumption no longer has to be restricted. It turns out they cholesterol along with other molecules “bandage up” injuries along the blood vessel walls caused by inflammation. Cholesterol levels are moreso a marker of inflammation and eating more cholesterol does not raised blood cholesterol levels [16].
In fact cholesterol has some benefits including cell communication, detoxification [17], and even protection of infection and cancers
[1], [2], [3], [4], [5].
Cholesterol is very important for MS as it’s the rate limiting (most important) factor for myelination
[6], [7], [8]. MS also commonly involves underlying chronic infection including Epstein Barr virus [9] [10] [11], candida [12], [13], [14] or bacterial pathogens.
So don’t skimp on the egg yolks, cheese or other A2 dairy
[15].

Personally, I found cholesterol including butter, ghee to be very helpful in giving making me feel better and healing me. Even now that I am a vegetarian, I get plenty of cholesterol from A2 Dairy.   





1.         U. Ravnskov, High cholesterol may protect against infections and atherosclerosis. QJM. 2003; 96: 927-934
2.         M.F. Muldoon, A. Marsland, J.D. Flory, B.S. Rabin, T.L. Whiteside and S.B. Manuck, Immune system differences in men with hypo- or hypercholesterolemia. Clin Immunol Immunopathol. 1997; 84: 145-149
3.         M. Gruber, M. Christ-Crain, D. Stolz, et al., Prognostic impact of plasma lipids in patients with lower respiratory tract infections - an observational study. Swiss Med Wkly. 2009; 139: 166-172
4.         A.A. Alsheikh-Ali, T.A. Trikalinos, D.M. Kent and R.H. Karas, Statins, low-density lipoprotein cholesterol, and risk of cancer. J Am Coll Cardiol. 2008; 52: 1141-1147
5.         H. Jafri, A.A. Alsheikh-Ali and R.H. Karas, Baseline and on-treatment high-density lipoprotein cholesterol and the risk of cancer in randomized controlled trials of lipid-altering therapy. J Am Coll Cardiol. 2010; 55: 2846-2854
6.         G. Saher, B. Brugger, C. Lappe-Siefke, et al., High cholesterol level is essential for myelin membrane growth. Nat Neurosci. 2005; 8: 468-475
7.         G. Saher, S. Quintes and K.A. Nave, Cholesterol: a novel regulatory role in myelin formation. Neuroscientist. 2011; 17: 79-93
8.         G. Saher and S.K. Stumpf, Cholesterol in myelin biogenesis and hypomyelinating disorders. Biochim Biophys Acta. 2015; 1851: 1083-1094
9.         A. Ascherio and K.L. Munger, Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann Neurol. 2007; 61: 288-299
10.       R.A. Farrell, D. Antony, G.R. Wall, et al., Humoral immune response to EBV in multiple sclerosis is associated with disease activity on MRI. Neurology. 2009; 73: 32-38
11.       K.L. Munger, L.I. Levin, E.J. O'Reilly, K.I. Falk and A. Ascherio, Anti-Epstein-Barr virus antibodies as serological markers of multiple sclerosis: a prospective study among United States military personnel. Mult Scler. 2011; 17: 1185-1193
12.       J. Benito-Leon, D. Pisa, R. Alonso, P. Calleja, M. Diaz-Sanchez and L. Carrasco, Association between multiple sclerosis and Candida species: evidence from a case-control study. Eur J Clin Microbiol Infect Dis. 2010; 29: 1139-1145
13.       D. Pisa, R. Alonso and L. Carrasco, Fungal infection in a patient with multiple sclerosis. Eur J Clin Microbiol Infect Dis. 2011; 30: 1173-1180
14.       D. Pisa, R. Alonso, F.J. Jimenez-Jimenez and L. Carrasco, Fungal infection in cerebrospinal fluid from some patients with multiple sclerosis. Eur J Clin Microbiol Infect Dis. 2013; 32: 795-801
15.       K. Woodford, Devil in the milk: illness, health and politics of A1 and A2 milk, Chelsea Green Pub (2007).


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